Genotype frequencies of polymorphic MDR1 variants in the Kazakhstani population

Introduction: Statins appear to be handled by an ATP-dependent membrane transporter and three SNPs (C1236T (rs1128503), G2677T (rs2032582), and C3435T (rs1045642), which capture the common genetic variation at this locus. Individuals, who carry the T allele at each SNP (i.e., the T-T-T haplotype), h...

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Main Authors: Samat Kozhakhmetov, Adil Supiyev, Almagul Kushugulova, Indira Tynybayeva, Alibek Kossumov, Leila Utepova, Saule Saduakhasova, Gulnara Shakhabayeva, Talgat Nurgozhin, Zhaxybay Zhumadilov
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2014-03-01
Series:Central Asian Journal of Global Health
Online Access:http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/118