Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase

Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase

The enzyme ADP-glucose pyrophosphorylase (ADP-Glc PPase) controls the biosynthesis of glycogen in bacteria and starch in plants. It is regulated by various activators in different organisms according to their metabolic characteristics. In Escherichia coli, the major allosteric activator is fructose...

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Bibliographic Details
Main Authors: Jaina A. Bhayani, Benjamin L. Hill, Anisha Sharma, Alberto A. Iglesias, Kenneth W. Olsen, Miguel A. Ballicora
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
allosteric regulation
polysaccharide biosynthesis
pyridoxal 5′-phosphate activation
sugar phosphate regulation
arginine scanning mutagenesis
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00089/full

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https://www.frontiersin.org/article/10.3389/fmolb.2019.00089/full

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