Proapoptotic <i>Bad</i> Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish

The BH3-only molecule Bad regulates cell death via its differential protein phosphorylation, but very few studies address its effect on early embryonic development in vertebrate systems. In this work, we examined the novel role of zebrafish Bad in the initial programmed cell death (PCD) for brain mo...

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Bibliographic Details
Main Authors: Jo-Chi Hung, Jen-Leih Wu, Jiann-Ruey Hong
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
bad
Online Access:https://www.mdpi.com/1422-0067/22/9/4832