A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.

A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metabolism. We used a neuronal-specific inhibition of miRNA matura...

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Bibliographic Details
Main Authors: Géraldine M Mang, Sylvain Pradervand, Ngoc-Hien Du, Alaaddin Bulak Arpat, Frédéric Preitner, Leonore Wigger, David Gatfield, Paul Franken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4309537?pdf=render

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http://europepmc.org/articles/PMC4309537?pdf=render

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