Pro-Inflammatory Effects of Indoxyl Sulfate in Mice: Impairment of Intestinal Homeostasis and Immune Response

Pro-Inflammatory Effects of Indoxyl Sulfate in Mice: Impairment of Intestinal Homeostasis and Immune Response

The intestines are recognized as the main source of chronic inflammation in chronic kidney disease (CKD) and, among other cells, macrophages are involved in modulating this process as well as in the impaired immune response which also occurs in CKD patients. In this study, we evaluated the effect of...

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Bibliographic Details
Main Authors: Shara Francesca Rapa, Francesco Prisco, Ada Popolo, Valentina Iovane, Giuseppina Autore, Biagio Raffaele Di Iorio, Fabrizio Dal Piaz, Orlando Paciello, Fuyu Nishijima, Stefania Marzocco
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
indoxyl sulfate
chronic kidney disease
intestinal inflammation
oxidative stress
intestinal epithelial cells
primary murine peritoneal macrophages
Online Access:https://www.mdpi.com/1422-0067/22/3/1135

Internet

https://www.mdpi.com/1422-0067/22/3/1135

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