Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.

It has been estimated that up to 30% of detectable polyps in patients regress spontaneously. One major challenge in the evaluation of effective therapy of cancer is the readout for tumor regression and favorable biological response to therapy. Inducible near infra-red (NIR) fluorescent probes were u...

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Bibliographic Details
Main Authors: Elias Gounaris, Ching H Tung, Clifford Restaino, René Maehr, Rainer Kohler, Johanna A Joyce, Hidde L Ploegh, Terrence A Barrett, Ralph Weissleder, Khashayarsha Khazaie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2488397?pdf=render