“Teaching old dogs new tricks”: targeting neural extracellular matrix for normal and pathological aging-related cognitive decline

“Teaching old dogs new tricks”: targeting neural extracellular matrix for normal and pathological aging-related cognitive decline

Cognitive decline is a feature of normal and pathological aging. As the proportion of the global aged population continues to grow, it is imperative to understand the molecular and cellular substrates of cognitive aging for therapeutic discovery. This review focuses on the critical role of neural ex...

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Bibliographic Details
Main Authors: Adam D Richard, Xiao-Hong Lu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
aging; cognitive decline; neural extracellular matrix; tetrapartite synapse; long-term memory storage; therapeutic targeting; striatum; chondroitin sulfate proteoglycan
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=4;spage=578;epage=581;aulast=Richard

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=4;spage=578;epage=581;aulast=Richard

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