Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity

Exploiting Surface Plasmon Resonance (SPR) Technology for the Identification of Fibroblast Growth Factor-2 (FGF2) Antagonists Endowed with Antiangiogenic Activity

Angiogenesis, the process of new blood vessel formation, is implicated in various physiological/pathological conditions, including embryonic development, inflammation and tumor growth. Fibroblast growth factor-2 (FGF2) is a heparin-binding angiogenic growth factor involved in various physiopathologi...

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Bibliographic Details
Main Authors: Marco Presta, Laura E. Depero, Paolo Bergese, Daria Leali, Stefania Mitola, Antonella Bugatti, Marco Rusnati
Format: Article
Language:English
Published: MDPI AG 2009-08-01
Series:Sensors
Subjects:
angiogenesis
fibroblast growth factor-2
heparan-sulfate proteoglycans
heparin
interactions
pentraxin 3
peptides
surface plasmon resonance
thrombospondin-1
Online Access:http://www.mdpi.com/1424-8220/9/8/6471/

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http://www.mdpi.com/1424-8220/9/8/6471/

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