Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats

Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats

Abstract Background Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac remodeling after heart injury. However, whether macrophage influence fib...

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Bibliographic Details
Main Authors: Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge Jin, Qing-Qing Wu, Sha-Sha Wang, Yuan Yuan
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Berberine
Cardiac fibrosis
Macrophage
Fibroblast
TGF-β1
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12872-019-1198-9

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http://link.springer.com/article/10.1186/s12872-019-1198-9

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