Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

Abstract Background Neurons are highly polarized cells consisting of three distinct functional domains: the cell body (and associated dendrites), the axon and the synapse. Previously, it was believed that the clinical phenotypes of neurodegenerative diseases were caused by the loss of entire neurons...

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Bibliographic Details
Main Authors: Laura C. Graham, Samantha L. Eaton, Paula J. Brunton, Abdelmadjid Atrih, Colin Smith, Douglas J. Lamont, Thomas H. Gillingwater, Giuseppa Pennetta, Paul Skehel, Thomas M. Wishart
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Molecular Neurodegeneration
Subjects:
Synapse
Mitochondria
Proteomics
Neuron
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s13024-017-0221-9

Internet

http://link.springer.com/article/10.1186/s13024-017-0221-9

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