GATA3 haploinsufficiency causes a rapid deterioration of distortion product otoacoustic emissions (DPOAEs) in mice

GATA3 haploinsufficiency causes a rapid deterioration of distortion product otoacoustic emissions (DPOAEs) in mice

Human HDR (hypoparathyroidism, deafness and renal dysplasia)-syndrome is caused by haploinsufficiency of zinc-finger transcription factor GATA3. The hearing loss due to GATA3 haploinsufficiency has been shown to be peripheral in origin, but it is unclear to what extent potential aberrations in the o...

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Bibliographic Details
Main Authors: M.A.J. van Looij, H. van der Burg, R.S. van der Giessen, M.M. de Ruiter, J. van der Wees, J.H. van Doorninck, C.I. De Zeeuw, G.A. van Zanten
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Neurobiology of Disease
Subjects:
DPOAE
OHC
Vacuole
HDR-syndrome
EM
Hearing loss
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001592

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http://www.sciencedirect.com/science/article/pii/S0969996105001592

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