Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus

<p>Abstract</p> <p>To elucidate the relationship between resistance to HRSV neutralizing antibodies directed against the F protein and the fusion activity of the F protein, a recombinant approach was used to generate a panel of mutations in the major antigenic sites of the F protei...

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Bibliographic Details
Main Authors: Sarisky Robert T, Gutshall Lester L, Branigan Patrick J, Day Nicole D, Liu Changbao, Del Vecchio Alfred M
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/71