Botulinum toxin A injection for chronic anal fissures and anal sphincter spasm improves quality of life in recessive dystrophic epidermolysis bullosa

We report a 20-year-old female with generalized, severe, recessive dystrophic epidermolysis bullosa who developed secondary chronic anal fissures. This resulted in anal sphincter spasm and severe, disabling pain. She was treated with five botulinum toxin A injections into the internal anal sphincter...

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Bibliographic Details
Main Authors: Cassandra Chaptini, MBBS, Genevieve Casey, MBBS, Adam G. Harris, MBChB, David Wattchow, FRACS, Lynne Gordon, FACD, Dedee F. Murrell, MA, BMBCh, FAAD, MD, FACD, FRCP
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:International Journal of Women's Dermatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352647515000507