Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells

Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells

It has been recognized that cancer stem-like cells (CSCs) in tumor tissue crucially contribute to therapeutic failure, resulting in a high mortality rate in lung cancer patients. Due to their stem-like features of self-renewal and tumor formation, CSCs can lead to drug resistance and tumor recurrenc...

Full description

Bibliographic Details
Main Authors: Somruethai Sumkhemthong, Supakarn Chamni, Gea U. Ecoy, Pornchanok Taweecheep, Khanit Suwanborirux, Eakachai Prompetchara, Pithi Chanvorachote, Chatchai Chaotham
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Marine Drugs
Subjects:
cancer stem-like cells
cisplatin
lung cancer
jorunnamycin A
stemness transcription factors
β-catenin
Online Access:https://www.mdpi.com/1660-3397/19/5/261

Internet

https://www.mdpi.com/1660-3397/19/5/261

Similar Items