Unique Regulation of Enterocyte Brush Border Membrane Na-Glutamine and Na-Alanine Co-Transport by Peroxynitrite during Chronic Intestinal Inflammation

Unique Regulation of Enterocyte Brush Border Membrane Na-Glutamine and Na-Alanine Co-Transport by Peroxynitrite during Chronic Intestinal Inflammation

Na-amino acid co-transporters (NaAAcT) are uniquely affected in rabbit intestinal villus cell brush border membrane (BBM) during chronic intestinal inflammation. Specifically, Na-alanine co-transport (ASCT1) is inhibited secondary to a reduction in the affinity of the co-transporter for alanine, whe...

Full description

Bibliographic Details
Main Authors: Subha Arthur, Palanikumar Manoharan, Shanmuga Sundaram, M Motiur Rahman, Balasubramanian Palaniappan, Uma Sundaram
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
peroxynitrite
chronic intestinal inflammation
Na-amino acid co-transport
ASCT1
B0AT1
Online Access:https://www.mdpi.com/1422-0067/20/6/1504

Internet

https://www.mdpi.com/1422-0067/20/6/1504

Similar Items