PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure

PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure

Though homotypic cell-in-cell (hoCIC) structures are implicated in the development and progression of multiple human tumors, the molecular mechanisms underlying their formation remain poorly understood. We found that the expression of Protocadherin-7 (PCDH7), an integral membrane protein, was negati...

Full description

Bibliographic Details
Main Authors: Chenxi Wang, Ang Chen, Banzhan Ruan, Zubiao Niu, Yan Su, Hongquan Qin, You Zheng, Bo Zhang, Lihua Gao, Zhaolie Chen, Hongyan Huang, Xiaoning Wang, Qiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PCDH7
cell-in-cell structure
adherens junctions
actomyosin
pMLC2
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00329/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00329/full

Similar Items