MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.

MicroRNAs have been shown to be important regulators of inflammatory and immune responses and are implicated in several immune disorders including systemic lupus erythematosus and rheumatoid arthritis, but their role in Lyme borreliosis remains unknown. We performed a microarray screen for expressio...

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Bibliographic Details
Main Authors: Robert B Lochhead, Ying Ma, James F Zachary, David Baltimore, Jimmy L Zhao, John H Weis, Ryan M O'Connell, Janis J Weis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4072785?pdf=render