Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family.

Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family.

Recently, the epidermal growth factor (EGF) receptor (EGFR), a member of the ErbB receptor family, and its down-stream signalling have been identified as co-factors for HCV entry and replication. Since EGFR also functions as a heterodimer with other ErbB receptor family members, the subject of the p...

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Bibliographic Details
Main Authors: Sabine Stindt, Patricia Cebula, Ute Albrecht, Verena Keitel, Jan Schulte am Esch, Wolfram T Knoefel, Ralf Bartenschlager, Dieter Häussinger, Johannes G Bode
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4757098?pdf=render

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http://europepmc.org/articles/PMC4757098?pdf=render

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