Pathophysiology and therapeutic potential of cardiac fibrosis

Abstract Inflammatory and fibrotic responses to myocardial damage are essential for cardiac repair; however, these responses often result in extensive fibrotic remodeling with impaired systolic function. Recent reports have suggested that such acute phase responses provide a favorable environment fo...

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Bibliographic Details
Main Authors: Hironori Hara, Norifumi Takeda, Issei Komuro
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Inflammation and Regeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41232-017-0046-5