Efficiency, selectivity, and robustness of nucleocytoplasmic transport.
All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. NPC-associated proteins containing phenylalanine-glycine repeats (FG nups) have large, flexible, unstructured proteinaceous regions, and line...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1914370?pdf=render |