OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation

OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation

BackgroundX-linked intellectual disability (XLID), which occurs predominantly in males, is a relatively common and genetically heterogeneous disorder in which over 100 mutated genes have been reported. The OTUD5 gene at Xp11.23 encodes ovarian tumor deubiquitinase 5 protein, which is a deubiquitinat...

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Main Authors: Ken Saida, Tokiko Fukuda, Daryl A. Scott, Toru Sengoku, Kazuhiro Ogata, Annarita Nicosia, Andres Hernandez-Garcia, Seema R. Lalani, Mahshid S. Azamian, Haley Streff, Pengfei Liu, Hongzheng Dai, Takeshi Mizuguchi, Satoko Miyatake, Miki Asahina, Tsutomu Ogata, Noriko Miyake, Naomichi Matsumoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
OTUD5
X-linked intellectual disability
LINKED syndrome
deubiquitinase
congenital malformation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.631428/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.631428/full

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