Dynamic changes of the phosphoproteome in postmortem mouse brains.

Protein phosphorylation is deeply involved in the pathological mechanism of various neurodegenerative disorders. However, in human pathological samples, phosphorylation can be modified during preservation by postmortem factors such as time and temperature. Postmortem changes may also differ among pr...

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Bibliographic Details
Main Authors: Tsutomu Oka, Kazuhiko Tagawa, Hikaru Ito, Hitoshi Okazawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120861?pdf=render