Mutational screening of the negative regulatory region of astrocyte elevated gene-1 promoter in hepatocellular carcinoma patients

Mutational screening of the negative regulatory region of astrocyte elevated gene-1 promoter in hepatocellular carcinoma patients

Astrocyte elevated gene-1 (AEG-1) is a positive regulator of tumorigenesis in human cancer cells. Human AEG-1 gene is located in chromosome 8q22 having 12 exons/11 introns. Chromosome 8q22 is known to be a hot spot for genomic alterations in several cancerous cells involving HCC. The aim of the stud...

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Bibliographic Details
Main Authors: Naghmeh Gholipour, Sakineh Mashjoor, Zeinab Emruzi Tubkanlu, Hamideh Khajeh, Malihe Naderi, Nader Mansour Samaei, Gholamreza Motalleb
Format: Article
Language:English
Published: Universidade Federal de Uberlândia 2018-10-01
Series:Bioscience Journal
Subjects:
astrocyte elevated gene -1
hepatocellular carcinoma
mutation
promoter
regulatory region
Online Access:http://www.seer.ufu.br/index.php/biosciencejournal/article/view/42617

Internet

http://www.seer.ufu.br/index.php/biosciencejournal/article/view/42617

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