Levels of Circulating MMCN-151, a Degradation Product of Mimecan, Reflect Pathological Extracellular Matrix Remodeling in Apolipoprotein E Knockout Mice

Aim Arterial extracellular matrix (ECM) remodeling by matrix metalloproteinases (MMPs) is one of the major hallmarks of atherosclerosis. Mimecan, also known as osteoglycin has been implicated in the integrity of the ECM. This study assessed the validity of an enzyme-linked immunosorbent assay (ELISA...

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Bibliographic Details
Main Authors: N. Barascuk, E. Vassiliadis, Q. Zheng, Y. Wang, W. Wang, L. Larsen, L.M. Rasmussen, M.A. Karsdal
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S7777