Predictable repeatability issues with GeneXpert-Xpert MTB/RIF (version 4) derived rifampicin resistant tuberculosis results from South India: Appreciating the limits of a technological marvel!

Predictable repeatability issues with GeneXpert-Xpert MTB/RIF (version 4) derived rifampicin resistant tuberculosis results from South India: Appreciating the limits of a technological marvel!

Background: GeneXpert MTB/RIF (Xpert), the fully automated cartridge-based nucleic acid amplification test for simultaneous identification of Mycobacterium tuberculosis complex and rifampicin resistance (RR), directly from samples is considered as a game changer for tuberculosis (TB) control program...

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Bibliographic Details
Main Authors: Praveen Sanker, Ramya Puthukkudi Kottuthodi, Anusree Puthenveettil Ambika, Vishnu T Santhosh, Ravikrishnan Balakrishnan, Sunil Kumar Mrithunjayan, Hisham Moosan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Biomedical and Biotechnology Research Journal
Subjects:
Delayed amplification
limits of Xpert
line probe assay
low bacterial load samples
negative probe-analyte result
positive probe-analyte result
repeatability
rifampicin false resistant
Xpert
Online Access:http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2017;volume=1;issue=1;spage=76;epage=80;aulast=Sanker

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http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2017;volume=1;issue=1;spage=76;epage=80;aulast=Sanker

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