Long noncoding RNA functionality in imprinted domain regulation.

Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription to predominantly one parental allele. Since the discovery of the first long noncoding RNA (lncRNA), which notably was an imprinted lncRNA, a body of knowledge has demonstrated pivotal roles for imprinted lncRN...

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Bibliographic Details
Main Authors: William A MacDonald, Mellissa R W Mann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008930