Everolimus treatment for neuroendocrine tumors: latest results and clinical potential
Neuroendocrine tumors (NETs) are a heterogeneous class of diseases characterized by challenging management. Preclinical evidence shows that the PI3K/AKT/mTOR signaling pathway plays a central role in the pathogenesis and progression of NETs. Everolimus is a direct inhibitor of this pathway, and ther...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-03-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758834016683905 |