An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics

Abstract Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the tissue, whereby current models do not effe...

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Bibliographic Details
Main Authors: Elisabeth A. Slade, Robin M. S. Thorn, Amber Young, Darren M. Reynolds
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-019-1682-5