An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics
Abstract Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the tissue, whereby current models do not effe...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Microbiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12866-019-1682-5 |