Dengue serotype cross-reactive, anti-E protein antibodies confound specific immune memory for one year after infection

Dengue serotype cross-reactive, anti-E protein antibodies confound specific immune memory for one year after infection

Dengue virus has four serotypes and is endemic globally in tropical countries. Neither a specific treatment nor an approved vaccine is available, and correlates of protection are not established. The standard neutralization assay cannot differentiate between serotype-specific and serotype cross-reac...

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Bibliographic Details
Main Authors: Ying Xiu eToh, Victor eGan, Thavamalar eBalakrishnan, Roland eZuest, Michael ePoidinger, Solomonraj eWilson, Ramapraba eAppanna, Tun Linn eThein, Adrian Keng-Yeow Ong, Lee Ching eNg, Yee Sin eLeo, Katja eFink
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Immunology
Subjects:
Antibodies
Dengue
Longitudinal Studies
Vaccines
B cells
viral infection
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00388/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00388/full

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