Emerging Therapeutic Strategies to Restore Regulatory T Cell Control of Islet Autoimmunity in Type 1 Diabetes

Emerging Therapeutic Strategies to Restore Regulatory T Cell Control of Islet Autoimmunity in Type 1 Diabetes

Despite many decades of investigation uncovering the autoimmune mechanisms underlying Type 1 Diabetes (T1D), translating these findings into effective therapeutics has proven extremely challenging. T1D is caused by autoreactive T cells that become inappropriately activated and kill the β cells in th...

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Bibliographic Details
Main Authors: Victoria Volfson-Sedletsky, Albert Jones, Jaileene Hernandez-Escalante, Hans Dooms
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
type 1 diabetes (T1D)
immunotherapy
autoimmune disease (AD)
T cells
Tregs (regulatory T cells)
nanotechnology/nanomaterials
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.635767/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.635767/full

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