New approaches to the synthesis of diclofenac choline

The process described herein proceeds to obtaining diclofenac choline from choline bicarbonate and diclofenac acid in mild conditions, using non-toxic solvent, with the same impurity profile deriving from diclofenac particle as for diclofenac sodium EP. The substance is also substantially free from...

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Bibliographic Details
Main Authors: Elżbieta Dąbrowska-Maś, Wojciech Raś
Format: Article
Language:English
Published: Growing Science 2017-07-01
Series:Current Chemistry Letters
Subjects:
Online Access:http://www.growingscience.com/ccl/Vol6/ccl_2017_11.pdf