Abnormal hippocampal BDNF and miR-16 expression is associated with depression-like behaviors induced by stress during early life.

Some environmental stressors lead to the onset of depression via inhibiting hippocampal BDNF expression, but other environmental stressors-induced depression exhibits no change in BDNF expression. The underlying mechanisms behind the divergence remain unknown. In this study, depression-like behavior...

Full description

Bibliographic Details
Main Authors: Mei Bai, Xiongzhao Zhu, Yi Zhang, Sheng Zhang, Li Zhang, Liang Xue, Jinyao Yi, Shuqiao Yao, Xiuwu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466179?pdf=render