HIV/SIV infection primes monocytes and dendritic cells for apoptosis.

HIV/SIV infection primes monocytes and dendritic cells for apoptosis.

Subversion or exacerbation of antigen-presenting cells (APC) death modulates host/pathogen equilibrium. We demonstrated during in vitro differentiation of monocyte-derived macrophages and monocyte-derived dendritic cells (DCs) that HIV sensitizes the cells to undergo apoptosis in response to TRAIL a...

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Bibliographic Details
Main Authors: Mireille Laforge, Laure Campillo-Gimenez, Valérie Monceaux, Marie-Christine Cumont, Bruno Hurtrel, Jacques Corbeil, John Zaunders, Carole Elbim, Jérôme Estaquier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21731488/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21731488/pdf/?tool=EBI

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