Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line.
Self-renewing organs often experience a decline in function in the course of aging. It is unclear whether chronological age or external factors control this decline, or whether it is driven by stem cell self-renewal-for example, because cycling cells exhaust their replicative capacity and become sen...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-04-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4831802?pdf=render |