Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line.

Self-renewing organs often experience a decline in function in the course of aging. It is unclear whether chronological age or external factors control this decline, or whether it is driven by stem cell self-renewal-for example, because cycling cells exhaust their replicative capacity and become sen...

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Bibliographic Details
Main Authors: Amanda Cinquin, Michael Chiang, Adrian Paz, Sam Hallman, Oliver Yuan, Indre Vysniauskaite, Charless C Fowlkes, Olivier Cinquin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4831802?pdf=render