Prostacyclin Inhibits Non-Small Cell Lung Cancer Growth by a Frizzled 9-Dependent Pathway That Is Blocked by Secreted Frizzled-Related Protein 1

Prostacyclin Inhibits Non-Small Cell Lung Cancer Growth by a Frizzled 9-Dependent Pathway That Is Blocked by Secreted Frizzled-Related Protein 1

The goal of this study was to assess the ability of iloprost, an orally active prostacyclin analog, to inhibit transformed growth of human non-small cell lung cancer (NSCLC) and to define the mechanism of iloprost's tumor suppressive effects. In a panel of NSCLC cell lines, the ability of ilop...

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Bibliographic Details
Main Authors: Meredith A. Tennis, Michelle Van Scoyk, Lynn E. Heasley, Katherine Vandervest, Mary Weiser-Evans, Scott Freeman, Robert L. Keith, Pete Simpson, Raphael A. Nemenoff, Robert A. Winn
Format: Article
Language:English
Published: Elsevier 2010-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610801034

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http://www.sciencedirect.com/science/article/pii/S1476558610801034

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