A Benchmark Side-by-Side Comparison of Two Well-Established Protocols for in vitro Hematopoietic Differentiation From Human Pluripotent Stem Cells

A Benchmark Side-by-Side Comparison of Two Well-Established Protocols for in vitro Hematopoietic Differentiation From Human Pluripotent Stem Cells

The generation of transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) remains challenging. Current differentiation protocols from hPSCs generate mostly hematopoietic progenitors of the primitive HSC-independent program, and it remains unclear what is the best com...

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Bibliographic Details
Main Authors: Francisco Gutierrez-Agüera, Virginia Rodriguez-Cortez, Paolo Petazzi, Clara Bueno, Pablo Menendez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
HPSC
hematopoiesis
differentiation
cytokines
WNT/B-CATENIN
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.636704/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.636704/full

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