Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo.

Post-transcriptional mRNA regulation by RNA binding proteins (RBPs) associated with AU-rich elements (AREs) present in the 3' untranslated region (3'UTR) of specific mRNAs modulates transcript stability and translation in eukaryotic cells. Here we have functionally characterised the import...

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Bibliographic Details
Main Authors: Manuel D Díaz-Muñoz, Sarah E Bell, Martin Turner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4332480?pdf=render