Genome-wide transcriptional profiling reveals two distinct outcomes in central Nervous system infections of rabies virus

Genome-wide transcriptional profiling reveals two distinct outcomes in central Nervous system infections of rabies virus

Rabies remains a major public health concern in many developing countries. The precise neuropathogenesis of rabies is unknown, though it is hypothesized to be due to neuronal death or dysfunction. Mice that received intranasal inoculation of an attenuated rabies virus (RABV) strain HEP-Flury exhibit...

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Bibliographic Details
Main Authors: Daiting eZhang, Feilong eHe, Shuilian eBi, Huixia eGuo, Baoshi eZhang, Fan eWu, Jiaqi eLiang, Youtian eYang, Qin eTian, Chunmei eJu, Huiying eFan, Jinding eChen, Xiaofeng eGuo, Yongwen eLuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Rabies virus
Transcriptome
innate immunity
Pathogenesis
MHC class II
pathogenic and attenuated strains
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00751/full

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http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00751/full

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