Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus

Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus

The identification of distinct and more efficacious antidepressant treatments is highly needed. Nitrous oxide (N2O) is an N-methyl-D-aspartic acid (NMDA) antagonist that has been reported to exhibit antidepressant effects in treatment-resistant depression (TRD) patients. Yet, no studies have investi...

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Bibliographic Details
Main Authors: Farah Chamaa, Hisham F. Bahmad, Ahmad-Kareem Makkawi, Reda M. Chalhoub, Elie D. Al-Chaer, George B. Bikhazi, Ziad Nahas, Wassim Abou-Kheir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
nitrous oxide
anesthetics
depression
neurogenesis
dentate gyrus
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00135/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00135/full

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