IL-33 increases ST2+ Tregs and promotes metastatic tumour growth in the lungs in an amphiregulin-dependent manner

IL-33 increases ST2+ Tregs and promotes metastatic tumour growth in the lungs in an amphiregulin-dependent manner

Regulatory T cells (Tregs) facilitate primary and metastatic tumour growth through the suppression of anti-tumour immunity. Emerging evidence suggests a distinct role for Tregs in mediating tissue repair and barrier integrity in the lungs by IL-33 mediated production of the growth factor amphireguli...

Full description

Bibliographic Details
Main Authors: E.C. Halvorsen, S.E. Franks, B.J. Wadsworth, B.T. Harbourne, R.A. Cederberg, C.A. Steer, I. Martinez-Gonzalez, J. Calder, W.W. Lockwood, K.L. Bennewith
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:OncoImmunology
Subjects:
regulatory t cells
st2
il-33
amphiregulin
metastasis
breast cancer
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1527497

Internet

http://dx.doi.org/10.1080/2162402X.2018.1527497

Similar Items