Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1

Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1

Summary: The Hippo signaling pathway plays a key role in development and cancer progression. However, molecules that intrinsically inhibit this pathway are less well known. Here, we report that the focal adhesion molecule Kindlin-2 inhibits Hippo signaling by interacting with and degrading MOB1 and...

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Bibliographic Details
Main Authors: Jiagui Song, Tianzhuo Wang, Xiaochun Chi, Xiaofan Wei, Sidi Xu, Miao Yu, Huiying He, Ji Ma, Xueying Li, Juan Du, Xiaoran Sun, Yunling Wang, Jun Zhan, Hongquan Zhang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719315177

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http://www.sciencedirect.com/science/article/pii/S2211124719315177

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