Spatiotemporally controlled genetic perturbation for efficient large-scale studies of cell non-autonomous effects
Studies in genetic model organisms have revealed much about the development and pathology of complex tissues. Most have focused on cell-intrinsic gene functions and mechanisms. Much less is known about how transformed, or otherwise functionally disrupted, cells interact with healthy ones toward a fa...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-11-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/38393 |