A Novel pH-Tunable Secondary Conformation Containing Mixed Micellar System in Anticancer Treatment

In this study, for the first time, we precisely assembled the poly-γ-benzyl-l-glutamate and an amphiphilic copolymer d-α-tocopherol polyethylene glycol succinate into a mixed micellar system for the embedment of the anticancer drug doxorubicin. Importantly, the intracellular drug-r...

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Bibliographic Details
Main Authors: Fu-Ying Shih, Wen-Ping Jiang, Xiaojie Lin, Sheng-Chu Kuo, Guan-Jhong Huang, Yu-Chi Hou, Chih-Shiang Chang, Yang Liu, Yi-Ting Chiang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/2/503