Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review

Telomerase reverse transcriptase (TERT) is the catalytic subunit of the enzyme telomerase and is essential for telomerase activity. Upregulation of TERT expression and resulting telomerase activity occurs in the large majority of malignancies, including thyroid cancer. This upregulation results in c...

Full description

Bibliographic Details
Main Authors: Brittany A. McKelvey, Christopher B. Umbricht, Martha A. Zeiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00485/full