Rotavirus NSP1 Inhibits Type I and Type III Interferon Induction

Type I interferons (IFNs) are produced by most cells in response to virus infection and stimulate a program of anti-viral gene expression in neighboring cells to suppress virus replication. Type III IFNs have similar properties, however their effects are limited to epithelial cells at mucosal surfac...

Full description

Bibliographic Details
Main Authors: Gennaro Iaconis, Ben Jackson, Kay Childs, Mark Boyce, Stephen Goodbourn, Neil Blake, Miren Iturriza-Gomara, Julian Seago
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/4/589