CHRNA5/CHRNA3 gene cluster is a risk factor for lumbar disc herniation: a case-control study

CHRNA5/CHRNA3 gene cluster is a risk factor for lumbar disc herniation: a case-control study

Abstract Background Lumbar disc herniation, a type of chronic low back pain syndrome, is caused by the lumbar intervertebral disk degeneration. Genetic variation in the CHRNA5/CHRNA3 has shown strong associations with smoking-related diseases. This study’s aim is to test whether single-nucleotide po...

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Bibliographic Details
Main Authors: Xuejun Yang, Xiaodong Guo, Zhi Huang, Yifeng Da, Wenhua Xing, Feng Li, Manglai Li, Ke Sun, Haiyu Jia, Yong Zhu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Lumbar disc herniation
CHRNA5/CHRNA3
Susceptibility
Single-nucleotide polymorphism
Online Access:http://link.springer.com/article/10.1186/s13018-019-1254-2

Internet

http://link.springer.com/article/10.1186/s13018-019-1254-2

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