Enteric Glia Mediate Neuron Death in Colitis Through Purinergic Pathways That Require Connexin-43 and Nitric OxideSummary

Background & Aims: The concept of enteric glia as regulators of intestinal homeostasis is slowly gaining acceptance as a central concept in neurogastroenterology. Yet how glia contribute to intestinal disease is still poorly understood. Purines generated during inflammation drive enteric neuron...

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Bibliographic Details
Main Authors: Isola A.M. Brown, Jonathon L. McClain, Ralph E. Watson, Bhavik A. Patel, Brian D. Gulbransen
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15001526