Disturbance of copper homeostasis is a mechanism for homocysteine-induced vascular endothelial cell injury.

Elevation of serum homocysteine (Hcy) levels is a risk factor for cardiovascular diseases. Previous studies suggested that Hcy interferes with copper (Cu) metabolism in vascular endothelial cells. The present study was undertaken to test the hypothesis that Hcy-induced disturbance of Cu homeostasis...

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Bibliographic Details
Main Authors: Daoyin Dong, Biao Wang, Wen Yin, Xueqing Ding, Jingjing Yu, Y James Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3799909?pdf=render