Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels.

The functions of actin family members during development are poorly understood. To investigate the role of beta-actin in mammalian development, a beta-actin knockout mouse model was used. Homozygous beta-actin knockout mice are lethal at embryonic day (E)10.5. At E10.25 beta-actin knockout embryos a...

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Bibliographic Details
Main Authors: Davina Tondeleir, Benjamin Drogat, Karolina Slowicka, Karima Bakkali, Sonia Bartunkova, Steven Goossens, Jody J Haigh, Christophe Ampe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694046?pdf=render