Evolving principles underlying neural lineage conversion and their relevance for biomedical translation [version 1; peer review: 4 approved]

Scientific and technological advances of the past decade have shed light on the mechanisms underlying cell fate acquisition, including its transcriptional and epigenetic regulation during embryonic development. This knowledge has enabled us to purposefully engineer cell fates in vitro by manipulatin...

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Bibliographic Details
Main Authors: Lea Jessica Flitsch, Oliver Brüstle
Format: Article
Language:English
Published: F1000 Research Ltd 2019-08-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-1548/v1